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WorldCIST'19 - 7th World Conference on Information Systems and Technologies

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Providing Alternative Measures For Addressing Adverse Drug-drug Interactions

Clinical Practice Guidelines (CPGs) are documents used in daily clinical practice that provide advice on how to best diagnose and treat diseases in the form of a list of clinical recommendations. When simultaneously applying multiple CPGs to patients, this can lead to complex multiple drug regimens (polypharmacy) with the potential for harmful combinations of drugs. The need to address these adverse drug events calls forth for systems capable of not only automatically represent the common potential conflicts or interactions that can happen when merging CPGs but also systems capable of providing conflict-free alternatives. This paper presents a solution that represents CPGs as Computer-Interpretable Guidelines (CIGs) and allows the automatic identification of drug conflicts and the provision of alternative measures to resolve these conflicts.

António Silva
University of Minho
Portugal

Tiago Oliveira
National Institute of Informatics, Tokyo, Japan
Japan

Ken Satoh
National Institute of Informatics, Tokyo, Japan
Japan

Paulo Novais
University of Minho
Portugal

 


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